Link Between Depression and Anxiety
By the Ridge Way clinical team · Depression · 5 min read
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Part of our Depression articles. For evaluation and medication management, see depression care at Ridge Way.
Depression and anxiety often occur together. About one in three U.S. adolescents and adults experience an anxiety disorder at some point in their lives, and anxiety disorders often go hand in hand with depression. The two are distinct conditions, but their symptoms frequently overlap. That overlap can make diagnosis and treatment more complex.
This post explains how depression and anxiety are linked, how they interact, and how both are treated.
[Image: A woman reading at a library table by a window, smiling. Link between depression and anxiety.]

Understanding Depression and Anxiety
Depression is a mood disorder that affects how a person feels, thinks and handles daily activities. Symptoms include a persistent sad, anxious or “empty” mood and loss of interest or pleasure in activities. They also include fatigue, appetite changes, difficulty concentrating, and thoughts of death or suicide. If you have thoughts of suicide, call or text 988, or call 911 if you are in immediate danger.
Anxiety disorders involve more than occasional worry or fear. For people with these disorders, anxiety does not go away, is felt in many situations, and can get worse over time. Physical symptoms such as trembling, sweating, feeling out of breath, and muscle tension often come with these feelings.
Despite their differences, depression and anxiety often co-occur. People with generalized anxiety disorder may also have depression, other anxiety disorders or other conditions. Having both can make each one feel more intense.
How Depression and Anxiety Overlap
Depression and anxiety share many features, which helps explain why they so often occur together. NIMH lists a persistent “anxious” mood and feeling restless or on edge among the signs of depression. Both conditions can affect emotions, physical well-being and thinking.
One key area of overlap is energy and motivation. Depression often brings fatigue and low energy, making daily responsibilities harder. Anxiety can keep the mind and body on alert, which is tiring over time. Together, these effects can leave people feeling too anxious to relax and too drained to act.
Another overlap is negative thinking. Someone might fear they will fail at a task (anxiety) and also feel they are not good enough to succeed (depression). This combination can deepen feelings of despair.
The Cycle of Depression and Anxiety
When depression and anxiety occur together, they can reinforce each other. Here are some of the ways this can happen.
Emotional Toll
Constant worry can make low mood harder to shake. For instance, someone who is anxious about their performance at work may feel worse about themselves when they think they have fallen short. This feedback loop makes it harder to break free of either condition.
Cognitive Effects
Both conditions can affect concentration and decision-making. Depression can make it hard to concentrate, remember and make decisions. Anxiety fills the mind with fears about what might happen. Together, these effects can lead to indecision and putting things off.
Physical Symptoms
Anxiety can bring restlessness and muscle tension, and it can make it hard to fall or stay asleep. Sleep problems are also a symptom of depression. Poor sleep can make both conditions harder to manage.
Behavioral Impact
Anxiety may lead people to avoid things, such as social events or important tasks. Depression can add to this by reducing motivation and energy. Avoidance can deepen isolation and keep the cycle going.
Physical Symptoms of Co-Occurring Depression and Anxiety
When depression and anxiety occur together, the body often reflects the mind’s distress. Physical symptoms may include the following.
- Fatigue. Fatigue and lack of energy are symptoms of depression. People with generalized anxiety may also feel fatigued.
- Muscle tension and aches. Anxiety can cause muscle aches and tension. Depression can also cause aches and pains without a clear physical cause.
- Headaches. Headaches can occur with both depression and anxiety.
- Digestive problems. Anxiety can cause stomachaches. Depression can cause cramps or digestive problems and changes in appetite.
- Sleep problems. Anxiety can make it hard to fall or stay asleep. Depression can cause trouble sleeping, waking too early, or oversleeping.
These physical symptoms are part of living with depression and anxiety, not a side issue. Recognizing them as part of the condition can help people get the right care. Read more about the physical symptoms of depression.
What Causes Depression and Anxiety to Co-Occur?
Neither depression nor anxiety can be reduced to a simple chemical imbalance. Several kinds of factors may play a role.
- Biological and genetic factors. Research suggests genetic, biological, environmental and psychological factors play a role in depression. NIMH research on anxiety disorders also studies genetic and environmental factors and brain development.
- Stressful events. A traumatic event or a stressful environment may raise the risk of generalized anxiety disorder. For instance, losing a loved one may first cause anxiety about coping, followed by low mood as grief sets in.
- Psychological factors. Patterns such as negative thinking are part of both conditions and can make each one harder to break.
Strategies for Managing Depression and Anxiety
Having both depression and anxiety can feel overwhelming, but effective treatments are available. Treatment typically involves psychotherapy, medication or both.
Therapy
Cognitive behavioral therapy (CBT) is a leading therapy for both conditions. In CBT, people learn to challenge and change unhelpful thoughts and behaviors to improve their depressive and anxious feelings. Therapy is provided by a therapist. Ridge Way does not provide therapy, but our medical team can refer you to one.
Medication
SSRI and SNRI antidepressants are commonly used to treat depression, and many of the same medications are used to treat anxiety. Antidepressants work by changing how the brain produces or uses certain chemicals involved in mood or stress. Read more about how antidepressant medication is used.
Healthy Habits
Healthy habits can support treatment. NIMH suggests physical activity, such as 30 minutes of walking a day, a regular bedtime and wake-up time, and regular, healthy meals.
Stress Management
Stress management techniques, such as exercise, mindfulness and meditation, can also reduce anxiety symptoms.
Building a Support Network
Spending time with trusted friends and family can help. Some people with anxiety disorders also benefit from joining a self-help or support group and sharing their experiences.
When to Get Help
Consider an evaluation when symptoms of depression or anxiety get in the way of work, school, relationships or daily life. The same is true when changes in mood, interest, sleep, appetite, energy or focus last two weeks or longer. You can take our depression screening or anxiety screening as a starting point.
Ridge Way provides psychiatric evaluation and medication management for adults, teens and children age six and older, in Sugar Hill and by telehealth across Georgia. We do not provide therapy. When therapy would help, our medical team can refer you to a therapist.
You do not need a referral unless your insurance plan requires one. Request an appointment and we will usually call you back within one business day.
Ridge Way is not an emergency service. If someone is in immediate danger, call 911. For a mental health or suicide crisis, call or text 988, any time, or call the Georgia Crisis and Access Line at 1-800-715-4225. See our crisis resources.
References
- National Institute of Mental Health. Depression, NIH Publication No. 24-MH-8079. Revised 2024. Accessed October 2026.
- National Institute of Mental Health. Anxiety Disorders. Last reviewed December 2024. Accessed October 2026.
- National Institute of Mental Health. Generalized Anxiety Disorder, When Worry Gets Out of Control. Revised 2025. Accessed October 2026.
- National Institute of Mental Health. Mental Health Medications. Last reviewed December 2023. Accessed October 2026.
- Centers for Disease Control and Prevention. Depression and Anxiety. Last reviewed October 13, 2023. Accessed October 2026.
Medical disclaimer: This article is for informational purposes only and does not replace medical advice, diagnosis or treatment. It cannot account for your history, what else you take, or what is actually going on. Ridge Way Mental Health Services does not provide therapy or counseling. If you are having thoughts of harming yourself, call or text 988, or call 911 if you are in immediate danger.
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